Clinical Trials

A Phase I, Open-label, Multicentre, Dose Escalation Study to Assess Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects with Advanced Solid Malignancies

A Randomized, Open-label Phase 3 Study in Patients With Newly Diagnosed Multiple Myeloma

The intravenous treatment’s influence on the mortality and morbidity from cardiovascular causes, and on the quality of life of patients with cardiac arrest and accompanying iron deficiency.

Pre-emptive therapy of minimal residual disease reappearanceor biochemical relapse in multiple myeloma

Drug registry with the analysis of treatment results in Polish patients with cutaneous T-cell lymphoma (CTCL).

An international, observational study based on secondary data describing the management and treatment in routine practice of patients with chronic kidney disease in central and eastern Europe.

A multicentre, randomized, placebo-controlled phase III study to compare efficacy and safety of Oral Drug ZX37200 in subject with depression.

Complimentary medical consultations

Phase 1 trial on the drug safety and pharmacokinetics in patients with relapsed or refractory B-cell acute lymphoblastic leukaemia.

Efficacy and safety of the drug in the first-line treatment of ALK-positive non-small cell lung cancer (NSCLC).

Early treatment in patients with idiopathic nephrotic syndrome.

Reperfusion thrombolytic therapy for ischaemic stroke in patients on the non-vitamin K antagonist oral anticoagulants

Efficiency and safety of consolidation treatment in patients with Hodgkin’s lymphoma (HL) undergoing autologous stem cell transplant (ASCT).

The influence of irreversible calcium electroporation, electrochemotherapy and electroporation on the quality of life and progression-free survival in patients with pancreatic cancer.

Evaluation of the therapeutic effect of a drug used in Polish patients with hereditary angioedema as part of the Drug Program.

Randomized, double-blind, placebo-controlled, parallel group multicenter study on the evaluation the efficacy and safety of drug treatment on the functions of pancreas beta cells in children and...

A medicine for PREVENTion of Myocardial Injury after Noncardiac Surgery

Safety and efficacy evaluation of two antiplatelet deescalating strategies in the acute coronary syndrome.

Preoperative intraperitoneal chemotherapy in hyperthermia complementing combined treatment in the advanced stomach cancer with high risk of a peritoneal relapse.

Phase II, Double blind, Randomized, Placebo controlled, Parallel group, Trial to Explore Efficacy, safety and pharmacokinetics of drug in Patients With an Acute Exacerbation of Schizophrenia

Comparison of the efficacy of two vitamin D3 doses in critically ill patients undergoing continuous renal replacement therapy.

Prospective, non-interventional observational study in patients with inflamed bowel disease receiving drug subcutaneously or intravenously to observe the choice of route of administration and...

Immunotherapy in the advanced, progressive cancer of the adrenal cortex treatment.

Actively monitoring stroke patients for spasticity.

Phase II, Double blind, Randomized, Placebo controlled, Parallel group, Trial to Explore the Potential Anti-dyskinetic Properties of a drug in Patients with Parkinson's Disease Suffering from drug...

Annual registry of Gram-negative infections in the Pediatric Intensive Care Units (PICUs) in Poland.

Neuroprotection in percutaneous occlusion of the left atrium appendage in patients with atrial fibrillation.

A single-center, randomized, open-label study to evaluate the safety and efficacy of renal artery denervation therapy with atrial fibrillation ablation in patients with atrial fibrillation and...

Chronic drug use as a prognostic factor for reduced susceptibility to SARS-CoV-2 virus infection in drug-exacerbated respiratory disease.

Implementation of lymphocytes in the treatment of adult patients with relapsed and refractory acute lymphoblastic leukemia. Phase I / II clinical trial.

Evaluation of the safety and effectiveness of the cardiac cryoablation system in the treatment of atrial fibrillation.

Neurostimulation for the treatment of post stroke aphasia

Real-world treatment outcomes in Polish patients with systemic lupus erythematosus (SLE). Multicenter, non-interventional study.

Multicenter, open-label, observational study assessing the effectiveness and safety of therapy in patients with high-risk non-muscle-invasive bladder cancer (HR/HG NMIBC)

Real-life treatment outcomes of monoclonal antibody IgG2/4K in Polish patients with paroxysmal nocturnal hemoglobinuria (PNH). Prospective and retrospective, multicenter, non-interventional study.

Medical Opinion Survey

Optimization of the heart failure with a reduced ejection fraction treatment - at discharge from hospital and at follow-up visits - patient education program and an observational study.

A non-interventional study to identify in vitro susCeptibiLity of bactErAial stRains isolated from patients with Cystic Fibrosis in Poland.

A review of therapeutic behaviors after introducing into the market a biosimilar drug.

The acceptance of oral carbonyl iron suspension in a group of paediatric patients requiring iron supplementation.

Educational platform for neonatologists.

ML40006 HEROLD A prospective, non-interventional study assessing the diagnostic, therapeutic proceedings and safety of anti-HER2 treatment in elderly patients (≥70 years old) with HER2 positive...

A multicentre, double-blind, randomised, placebo- controlled phase II study to assess efficacy, safety and pharmacokinetics of inhaled substance in subject with treatment-resistant bipolar depression

Multicentre, prospective clinical trial evaluating the possibility for a patient’s independent and safe decision regarding the use of a medicinal product for erectile dysfunction.

A multicenter, prospective clinical study that evaluate the possibility of making an independent and safe decision regarding the use of a medicinal product for erectile dysfunction

Evaluation of the effects of exacerbation of haemorrhoidal disease treatment using suppositories in combination with phlebotropic and local soothing treatments.

Identification of factors affecting the attractiveness of using insulin pumps used in the treatment of diabetic patients

Multicentre, open-label, randomized, non-commercial study to evaluate the efficacy and safety of a study substance in the outpatient COVID-19 treatment in combination with telemedicine care among...

A randomized, multicenter, placebo-controlled, double-blind study to determine the efficacy and safety of a cream containing Kalanchoe extract.

On the role of adherence to medical recommendations in the effective treatment of chronic cardiovascular and psychiatric diseases.

Prevention, diagnosis and control of the metabolic syndrome in psychotic patients.

Therapeutic trends in the treatment of depressive episodes in patients with symptoms of anhedonia, sleep and sexual dysfunction and lack of effectiveness of previous treatment.

Therapeutic concepts used in the treatment of psychotic disorders

Evaluation of the quality of the therapeutic process in the treatment of psoriasis as part of a routine medical practice.

Multicentre, prospective clinical trial evaluating the possibility for a patient’s independent and safe decision regarding the use of a medicinal product for erectile dysfunction.

Research on the needs and preferences of doctors in the treatment of severe and difficult asthma.

Less invasive administration of the surfactant in the treatment of neonatal respiratory distress syndrome in routine clinical practice.

Targin - efficacy and safety of treatment after conversion from previously used opioid in patients with cancer pain.

Application of immunoglobulins in Polish paediatric patients with primary and secondary immunodeficiencies.

Multicentre, randomized, double-blind, non-commercial clinical trial to evaluate the efficacy and safety of a specific anti-SARS-CoV-2 immunoglobulin in the treatment of COVID-19.

A multicentre, double-blind, randomised, placebo - controlled phase II study to assess efficacy, safety and pharmacokinetics of inhaled Esket...ine in subject with treatment-resistant depression in...

The influence of the Program 75+ on the neurological patients’ treatment in Poland.

The ultrasound image of the lungs in neonates with respiratory distress syndrome: analysis of the reproducibility and prognostic properties of the modified rating scale.

Clinical benefits of polytherapy with neuroleptics in the treatment of patients with psychotic disorders.

Observational study to evaluate the acceptability and bleeding profile with drug, in a regimen of use 24/4 in contraception after 5 cycles of use during breastfeeding.

The Use of Sedative Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST).

Feasibility of a software for analysis of Fourier Transform Infrared (FTIR) Spectroscopy analysis spectra of hair samples as a tool in breast cancer diagnosis.

LAAC registry Military Institute of Medicine

Hormone-dependent breast cancer. The essence of the choice of a therapeutic method in the anti-cancer treatment in women.

Physician preferences and therapeutic regimens used in the maintenance treatment of schizophrenia.

Non-interventional, observational, molecular response study in adult chronic myeloid leukaemia patients treated with second-line drug…

The analysis of therapeutic decisions in patients with depression qualifying for therapy with innovative antidepressants.

A prospective, single-arm, open, single-center study to assess efficacy. Patients with symptoms of dry eye disease.

Activity after kidney or liver transplant and psychophysical determinants of participation in social and professional life.

Application of convalescent plasma in the treatment of COVID-19 patients with metabolomic and laboratory evaluation of the progress of plasma therapy.

Randomized, Parallel-group, Double-blind, Comparative Bioequivalence Trial ofMabionCD20 (Mabion SA) Compared to original Hoffman-LaRoche) in Patients with Diffuse Large B-cell Lymphoma.

A randomized, double-blind, experimental study evaluating the efficiency and safety for the VGuard device in the treatment of mild cognitive impairment (MCI).

The impact of the patient's health status and the clinical course of the disease on therapeutic decisions in the treatment of severe depression, schizophrenia and bipolar disorder.

Clinical in vivo evaluation of the treatment solution for medical imaging in the infrared range of prick allergy skin tests…

Investigation on the therapeutic trends.

Assessment of changes in biological drug treatment and the challenges posed by physicians and patients in biological drug treatment in Poland.

Clinical perspective of the use of the solution for infusion in the treatment of ulcerative colitis. Multicentre observational study.

Determining the correlation between vital parameters - pressure, pulse, temperature, saturation and the risk of adverse events. Examination of UJCM patients.

Evaluation of drug programs B.32 (CD) and B.55 (UC).

Complimentary pulmonological consultations

Assessment of fatigue in the population of Polish patients with inflammatory bowel diseases (IBD). Collegium Medicum Bydgoszcz.

Effect of statin X treatment on cholesterol levels in patients after myocardial infarction.

The association between disease activity and quality of life, fatigue, mood and sleep disorders in patients with moderate or severe ulcerative colitis or Crohn’s disease… Prospective observational...

The efficiency of the combination of high drug doses in adults with uncontrolled asthma on moderate drug doses.

Assessment of the diagnostic strategy of Primary Immunodeficiency (PID) in adult patients

Non-interventional study with retrospective and prospective evaluation of clinical efficacy in monotherapy or in a routine combination therapy in relation to the combined administration of drugs as...

Uric acid measurement log UAVID

Treatment in children aged 6 – 18 years old with chronic hepatitis C using a pangenotypic drug with a direct antiviral activity.

A research experiment aimed at examining the effect of a low polyamine diet on the perception of neuropathic pain associated with cancer and/or cancer treatment in patients with cancer in remission.

Early treatment of heart failure: a non-interventional observational study in patients with heart failure and initiated treatment in CEE-BA.

A 12-week, phase II, multicentre, randomised, double blind, efficacy and safety study comparing CPL409116 to placebo, in combination with drug in participants with active rheumatoid arthritis who...

A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Evaluate Efficacy, Safety and Pharmacokinetics after 2-weeks Administration of drug in Subjects With Type 2...

Clinical characteristics associated with a favorable response to surfactant in premature infants ≥34 weeks of gestational age

Clinical efficiency of vendolizumab used in the Crohn’s disease treatment as part of the Drug Program. Prospective, observational study considering the fatigue and other…

The influence of the concentration/dose ratio and other clinical variables on kidney function in kidney transplant recipients. Non-interventional, prospective observational study

Evaluation of biological treatment’s distant effects in patients with ulcerative colitis in Poland. Non-interventional observational study